| Molecule ID | Mol1378 |
|---|---|
| Molecule name | Bufalin |
| Download structure (click to download) |  |
| Pharmacological and molecular properties | |
| InChIKey | QEEBRPGZBVVINN-BMPKRDENSA-N |
| Formular | C24H34O4 |
| Activity | in vitro, CHO cells; leukemia ML1 cells; KB, IC50=0.67μg/ml; HL-60, IC50<0.01μg/ml; MH-60, IC50>25μg/ml; HepG2, IC50=0.6±0.0μM; A549, IC50=0.6±0.1μM; (Control: doxorubicin, HepG2, IC50=0.3±0.1μM; A549, IC50=0.1±0.0μM); |
| CAS | ♦ 465-21-4 |
| Molecule synonyms | |
| Related targets | |
| Related Herbs | |
| Reference | [1] Tian H Y, Luo S L, Liu J S, et al. C23 steroids from the venom of Bufo bufo gargarizans [J]. Journal of natural products, 2013, 76(10): 1842-7. [2] Zhou, J., Xie, G. and Xinjian, Y. (2012) Anticancer active components in TCM. TCM series of active components. Science Press, Bei Jing. |