CancerHSP
Molecule Information
Molecule IDMol0196
Molecule namematrine
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Pharmacological and molecular properties
InChIKeyZSBXGIUJOOQZMP-KYEXWDHISA-N
FormularC15H24N2O
Activityin vitro, leukemia K562; gastric carcinoma cell; EAC in vitro and in vivo, Lewis lung cancer, S180; Sophoridine (SRI) significantly inhibited the growth of SW480 cells, and the administration of SRI significantly inhibited the growth of xenograft tumors without apparent toxicity.
CAS♦ 519-02-8
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Reference[1] Zhou, J., Xie, G. and Xinjian, Y. (2012) Anticancer active components in TCM. TCM series of active components. Science Press, Bei Jing.
[2] Liang L, Wang X Y, Zhang X H, et al. Sophoridine exerts an anti-colorectal carcinoma effect through apoptosis induction in vitro and in vivo[J]. Life sciences, 2012, 91(25): 1295-1303.
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